Steve Glover's departmental home page

Steve Glover's teaching and research home page

o      Mutagenicity of N-acyloxy-N-alkoxyamides as  probes for drug-DNA interactions.

A quantitative structure-activity relaationship as a pointer to how organic structures can influence DNA binding

o      SN2 Reactions at amide nitrogen - theoretical models for reactions of mutagenic N-acyloxy-N-alkoxyamides with bionucleophiles

Animations and hyperactive molecules for electronic journal article Arkivok 2001, Vol 2 issue 12

o      First crystal structures of anomeric amides

The recently obtained structure of an N-acyloxy-N-alkoxyamide depicts the most pyramidal tertiary amide structure to date. An N,N'-diacyl-N,N'-dialkoxyhydrazine also exhibits strongly pyramidal nitrogens due to anomeric substitution at the nitrogens.

o      The HERON rearrangement in an N-amino-N-alkoxyamide

Background and animation of this new reaction, now included in the 14th Edition of the Merck Index as a Named Reaction. 

o      A Dynamic NMR Investigation of the Conformational Isomerism in Novel 1,3,4,5-Tetrahydro-2,1-benzoxazepines

Contribution to the Electronic Conference on Heterocyclic Chemistry, Reaction Mechanisms and Conformation, paper 107 (for full functionality this page requires MDL's ChemScape CHIME plugin)

o      Mechanism of Nitrenium Ion Cyclisations in Formation of N-acyl-3,4-dihydro-1H-2,1-benzoxazines  and N-acyl-1,3,4,5-tetrahydro-2,1-benzoxazepines

Contribution to the Electronic Conference on Heterocyclic Chemistry, Reaction Mechanisms and Conformation, paper 102 (for full functionality this page requires MDL's ChemScape CHIME plugin)

 


 

These pages have been accessed hit countertimes since 08/08/07